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Testicular Biopsy

In a testicular biopsy, the surgeon takes a small piece of tissue from the testicle (the male reproductive organ positioned in the scrotum and responsible for the production of sperm).

One can use a biopsy of the testes for a variety of reasons, including finding the cause of a male infertility problem, getting sperm for in vitro conception, and many more.


A testicular biopsy can be performed in one of two ways.

Percutaneous Biopsy

A thin biopsy needle is used for a percutaneous biopsy and is inserted through the skin. The testicular tissue is collected and placed in the syringe at the tip of the needle. This treatment does not necessitate an incision or stitches. A “fine needle biopsy” is another name for this procedure. Core needle biopsy is a new variation of this method that uses a hollow needle to remove a cylinder of cells that is larger than the sample from a fine needle biopsy.

The percutaneous biopsy procedure depends on the type of needle used, either a core or a tiny needle. The surgeon inserts a needle into the testicle. When a surgeon performs a core needle biopsy, the tissue sample is extracted with a loud clicking sound. With a syringe and a fine needle, the tissue sample can be extracted fast. The second testicle is treated in the same manner.

Open Biopsy

An open biopsy, sometimes known as a surgical biopsy, is a common procedure. The surgeon will make an incision on your skin and your testicle. Then he’ll collect a piece of tissue from the wound and stitch it back together.

The doctor will create a small cut in your skin and then remove a small piece of testicular tissue; you may feel some discomfort, but it is unlikely that you will experience any pain. A single absorbable stitch is usually sufficient to close a testicular incision. Using a second stitch, the skin is closed. On the second testicle, the exact procedure is carried out.

Diagnostic Uses of a Testicular Biopsy

Testicular biopsies are used to rule out other causes of male infertility, including sperm infection. Sperm quality and quantity are taken into account in a semen analysis procedure. Masturbation is used to collect the first sample of semen.

A semen analysis can detect poor sperm quality, a lack of sperm, and abnormally low sperm counts in a person.

It’s possible that a testicular biopsy can also be performed to detect testicular cancer, identify the reason for a lump in one’s testis, and evaluate whether a blockage is the cause. IVF procedures use this technique to retrieve sperm.

About 15 to 20 minutes are needed for a testicular biopsy to be completed.

Testicular Biopsy: Recovery

Some specific instructions will be given to you by the surgeon in order to assist you in healing and to maintain your comfort. Depending on the type of biopsy, specific guidelines will be provided.

In most cases, the surgeon will tell you to abstain from sexual activity for at least two weeks and to keep the biopsy site dry, avoid washing it, and avoid taking aspirin for a week as part of your recovery process.

Discoloration and discoloration of the skin in the first few days is usual.

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